Response of alopecia areata of the beard to oral tofacitinib
نویسندگان
چکیده
منابع مشابه
Transient Efficacy of Tofacitinib in Alopecia Areata Universalis
Alopecia areata is a common autoimmune disorder that targets hair follicles. Swarms of lymphocytes surround the basis of the follicles, inducing loss of pigmented terminal hair and subsequently inhibit further hair growth. Depending on the extent of involvement, alopecia areata can be associated with a dramatic reduction of quality of life. Currently, no targeted treatment option is available, ...
متن کاملSafety and efficacy of the JAK inhibitor tofacitinib citrate in patients with alopecia areata.
BACKGROUND Alopecia areata (AA) is an autoimmune disease characterized by hair loss mediated by CD8+ T cells. There are no reliably effective therapies for AA. Based on recent developments in the understanding of the pathomechanism of AA, JAK inhibitors appear to be a therapeutic option; however, their efficacy for the treatment of AA has not been systematically examined. METHODS This was a 2...
متن کاملAlopecia areata.
n engl j med 367;3 nejm.org july 19, 2012 279 methacin should be used in addition to pancre atic stents in highrisk patients. However, post hoc analysis of our trial suggests that indometha cin may obviate the need for prophylactic pan creatic stent placement (unpublished data), and we therefore agree with Baron et al. that com parative effectiveness studies of indomethacin and pancreatic ...
متن کاملEfficacy of dinitrochlorobenzene in the treatment of alopecia areata
Background: Various kinds of sensitizers are administrated foralopecia areata treatment. The aim of this study was to evaluatetreatment response to Dinitrochlorobenzene (DNCB) in alopeciaareata patients.Method: In this study, 117 patients were treated with DNCBunder a specific checklist. All patients were sensitized with a 2%DNCB and then treated with ascending DNCB concentrations(0.001%-2%). R...
متن کاملManagement of alopecia areata
Epithelial Sciences, School of Translational Medicine, University of Manchester, Manchester Jackson Laboratory, Bar Harbor, ME, USA Department of Dermatology, China-Japan Union Hospital of JiLin University, Chang Chun, People’s Republic of China Department of Dermatology, University of Lübeck, D-23538 Lübeck, Germany Skin Disease Research Centre, Division of Dermatology, Vanderbilt Medical Cent...
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ژورنال
عنوان ژورنال: Journal of the American Academy of Dermatology
سال: 2020
ISSN: 0190-9622
DOI: 10.1016/j.jaad.2019.10.058